pentobarbital will lower the level or result of doxorubicin by impacting hepatic/intestinal enzyme CYP3A4 metabolism. Use Warning/Check.pentobarbital decreases outcomes of sufentanil SL by affecting hepatic/intestinal enzyme CYP3A4 metabolism. Modify Therapy/Observe Carefully. Coadministration of CYP3A4 inducers may decrease sufentanil ranges and e